Please join our excellent speakers who will discuss a range of topics related to the drug development and clinical trial process. From the underlying translational science to phase I trial design and beyond, to the incorporation of genomics and precision medicine in trials and in practice.

DATE: 1st Thursday of the month (unless otherwise specified)

TIME: 16:30 – 17:30 (Melbourne Time)

LOCATION: Online Webinar

The series will run across 2022/23

For enquiries, please contact Sathya Manoharan,  Early Drug Development Fellow (PeterMac 2022/23) on [email protected]

DateTopicSummary
21st July 2022Phase I Trial Design

(now available on-demand, password access only)

Jayesh Desai and Sophia Frentzas

Broad Overview of the Program

Introduction to Drug Development

Drug development trial design in 2022

Pharmacology/PD basics and applied sciences

4th Aug 2022Trials 101

(now available on-demand, password access only)

Ben Tran and Mark Voskoboynik

Patient selection, start dates and DLT period

Pre-consent and consent, eligibility

Nuances of escalation versus expansion

RECIST and irRECIST, AEs, SAEs and practical GCP issues

1st Sept 2022Kinase inhibition/targeting kinases: what makes a good oncogenic target?

Grant McArthur and Stephen Luen

Genomics in drug development / clinical practice

Kinase inhibitors vs cytotoxics vs IO from a drug Development perspective

6th Oct 2022Cancer Immunology: part 1

Paul Neeson and Stephen Luen

Underlying science

Potential targets/agents

3rd Nov 2022Cancer Immunology: part 2

Paul Neeson and Stephen Luen

Complex biomarkers
1st Dec 2022Genomics and Next Generation Sequencing

Kortnye Smith

Basic principles of precision medicine

Genomic testing options

Interpreting results: issues and challenges

Case studies